A simple imaging exam capable of assessing myocardial deformation during contraction has emerged as a promising tool for predicting the risk of cardiac complications in patients with chronic Chagas disease.

A European study has demonstrated a sustained long-term reduction in prostate cancer mortality through prostate-specific antigen (PSA) screening. However, the findings also highlight the issue of overdiagnosis, or the detection of slow-growing cancers that are unlikely to affect a patient's lifespan, associated with PSA screening. To address this concern, the researchers advocate the development of risk-based screening.

Long COVID is a heterogeneous clinical condition that affects thousands of people and can manifest in many different ways. Understanding why some people develop it while others do not remains one of the main scientific challenges.

Scientists at Wake Forest University School of Medicine have discovered a new way to kill cancer cells by blocking their ability to clean up harmful waste. Cancer cells produce high levels of hydrogen peroxide, which can damage them if it builds up. Normally, they rely on a special protein to keep this in check. The research team found a way to shut down that protein, causing toxic levels of hydrogen peroxide to overwhelm the cancer cells and destroy them, according to a study published in Science Advances.

Researchers from University of Tsukuba and their collaborators interviewed Japanese primary care physicians and subsequently identified six distinct categories of experiences contributing to their sense of "meaning" in their professional roles. Caring for patients with diverse health problems and complex backgrounds and making contributions to education and the community were among these experiences, which are expected to promote primary care physicians' career development. The findings are published in BMC Primary Care.